Compile Data Set for Download or QSAR
Report error Found 1159 of affinity data for UniProtKB/TrEMBL: Q16620
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0930nMAssay Description:Inhibition of human TRKB using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.100nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.100nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164901(US9067914, Ex. 3-15 | US10166239, Ex. 3-15 | US114...)
Affinity DataIC50: 0.100nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM769503((3R)-6-fluoro-11-(fluoromethyl)-3-methyl-10-oxa-2,...)
Affinity DataIC50: 0.170nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374713(US10246466, Example 20 | 11-fluoro-14-methyl-6,7,1...)
Affinity DataKd:  0.180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM374713(US10246466, Example 20 | 11-fluoro-14-methyl-6,7,1...)
Affinity DataKd:  0.180nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., A small molecule-kinase interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM50512464(CHEMBL4555442)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human GST-tagged TRKB (456 to 822) expressed in baculovirus expression system using TK-biotin peptide as substrate incubated for 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164945(US9067914, Ex. 3-40-5 | US10166239, Ex. 3-40-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164930(US9067914, Ex. 3-35-4 | US10166239, Ex. 3-35-4 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164931(US9067914, Ex. 3-35-5 | US10166239, Ex. 3-35-5 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164902(US9067914, Ex. 3-16 | US10166239, Ex. 3-16 | US114...)
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164928(US9067914, Ex. 3-35-2 | US10166239, Ex. 3-35-2 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164941(US9067914, Ex. 3-40-1 | US10166239, Ex. 3-40-1 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164943(US9067914, Ex. 3-40-3 | US10166239, Ex. 3-40-3 | U...)
Affinity DataIC50: 0.200nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM769504((3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- ...)
Affinity DataIC50: 0.25nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM769494((3R)-6-fluoro-3-methyl-10-oxa-2,13,17,18,21-pentaa...)
Affinity DataIC50: 0.290nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164929(US9067914, Ex. 3-35-3 | US10166239, Ex. 3-35-3 | U...)
Affinity DataIC50: 0.300nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164927(US9067914, Ex. 3-35-1 | US10166239, Ex. 3-35-1 | U...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164927(US9067914, Ex. 3-35-1 | US10166239, Ex. 3-35-1 | U...)
Affinity DataIC50: 0.300nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164944(US9067914, Ex. 3-40-4 | US10166239, Ex. 3-40-4 | U...)
Affinity DataIC50: 0.300nMAssay Description:In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164929(US9067914, Ex. 3-35-3 | US10166239, Ex. 3-35-3 | U...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164885(US9067914, Ex. 3-1 | US10166239, Ex. 3-1 | US11406...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of N-terminal GST tagged human TrkB cytoplasmic domain (456 to 822 amino acids) pre-incubated for 15 mins before peptide substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
First People's Hospital of Shangqiu

Curated by ChEMBL
LigandPNGBDBM164927(US9067914, Ex. 3-35-1 | US10166239, Ex. 3-35-1 | U...)
Affinity DataIC50: 0.300nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

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