Compile Data Set for Download or QSAR
Report error Found 297 of affinity data for UniProtKB/TrEMBL: Q16740
LigandChemical structure of BindingDB Monomer ID 50640862BDBM50640862(CHEMBL4303616)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human ClpP expressed in Escherichia coli using AC-WLA-AMC as substrate measured every 5 mins for 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606048BDBM50606048(DORDAVIPRONE | Dordaviprone | Onc 201 | Onc-201 | ...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human ClpP expressed in Escherichia coli using AC-WLA-AMC as substrate measured every 5 mins for 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50666752BDBM50666752(CHEMBL6177725)
Affinity DataEC50:  22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666771BDBM50666771(CHEMBL6172967)
Affinity DataEC50:  27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50640863BDBM50640863(CHEMBL5572211)
Affinity DataKd:  30nMAssay Description:Binding affinity to human ClpP expressed in Escherichia coli assessed as dissociation constant by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50666769BDBM50666769(CHEMBL6172944)
Affinity DataEC50:  43nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666774BDBM50666774(CHEMBL6177581)
Affinity DataEC50:  45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50648013BDBM50648013(CHEMBL5597011)
Affinity DataKd:  53nMAssay Description:Binding affinity to human recombinant N-terminal 6his/sumo tagged ClpP (57 to 277 residues) assessed as dissociation constant incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50666762BDBM50666762(CHEMBL6166703)
Affinity DataEC50:  56nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666772BDBM50666772(CHEMBL6167082)
Affinity DataEC50:  59nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666761BDBM50666761(CHEMBL6173060)
Affinity DataEC50:  63nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666751BDBM50666751(CHEMBL6172920)
Affinity DataEC50:  65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50666768BDBM50666768(CHEMBL6164875)
Affinity DataEC50:  68nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50648013BDBM50648013(CHEMBL5597011)
Affinity DataEC50:  80nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50666778BDBM50666778(CHEMBL6177210)
Affinity DataKd:  88nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50648014BDBM50648014(CHEMBL5596220)
Affinity DataEC50:  90nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50648012BDBM50648012(CHEMBL5597441)
Affinity DataEC50:  90nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50666776BDBM50666776(CHEMBL6170047)
Affinity DataEC50:  93nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50606073BDBM50606073(CHEMBL5170429)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606072BDBM50606072(CHEMBL5176506)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50666770BDBM50666770(CHEMBL6176209)
Affinity DataEC50:  113nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50648011BDBM50648011(CHEMBL5596597)
Affinity DataEC50:  120nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50230546BDBM50230546(CHEMBL5287429)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50230549BDBM50230549(CHEMBL5283010)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50230547BDBM50230547(CHEMBL5290620)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50606066BDBM50606066(CHEMBL5194447)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606077BDBM50606077(CHEMBL5180553)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50648009BDBM50648009(CHEMBL5598515)
Affinity DataEC50:  130nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50230548BDBM50230548(CHEMBL5275131)
Affinity DataEC50:  130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50648008BDBM50648008(CHEMBL5597008)
Affinity DataEC50:  130nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606065BDBM50606065(CHEMBL5173519)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50230548BDBM50230548(CHEMBL5275131)
Affinity DataEC50:  135nMAssay Description:Agonist activity at human recombinant CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50648010BDBM50648010(CHEMBL5597414)
Affinity DataEC50:  140nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630967BDBM50630967(CHEMBL5426567)
Affinity DataEC50:  140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50630967BDBM50630967(CHEMBL5426567)
Affinity DataEC50:  140nMAssay Description:Activation of recombinant human CLpP using casein-FITC as substrate preincubated for 30 mins followed by substrate addition by spectra max i3x fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50666760BDBM50666760(CHEMBL6176195)
Affinity DataEC50:  151nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50648013BDBM50648013(CHEMBL5597011)
Affinity DataKd:  155nMAssay Description:Binding affinity to ClpP in human MIA PaCa-2 cells assessed as dissociation constant at 67 degreeC measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  156nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50606084BDBM50606084(CHEMBL5205960)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606047BDBM50606047(CHEMBL5191392)
Affinity DataKd:  180nMAssay Description:Binding affinity to human CLpP assessed as dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50668653BDBM50668653(CHEMBL6192038)
Affinity DataKd:  181nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50668653BDBM50668653(CHEMBL6192038)
Affinity DataKd:  181nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50668653BDBM50668653(CHEMBL6192038)
Affinity DataKd:  181nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50606078BDBM50606078(CHEMBL5197418)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606047BDBM50606047(CHEMBL5191392)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50640863BDBM50640863(CHEMBL5572211)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human ClpP expressed in Escherichia coli using AC-WLA-AMC as substrate measured every 5 mins for 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50606086BDBM50606086(CHEMBL5196310)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50668653BDBM50668653(CHEMBL6192038)
Affinity DataEC50:  220nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50648005BDBM50648005(CHEMBL5597713)
Affinity DataEC50:  230nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50668646BDBM50668646(CHEMBL6192577)
Affinity DataEC50:  240nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
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