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Report error Found 1782 of affinity data for UniProtKB/TrEMBL: Q16769
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519291BDBM50519291(CHEMBL4462495 | US20240059675, Compound SEN177 | U...)
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of sQC (unknown origin) expressed in Escherichia coli Transetta (DE3) assessed as N-terminal pyroglutamate formation using fluorescent sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581458BDBM50581458(CHEMBL5092802)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581397BDBM50581397(CHEMBL5085353)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581442BDBM50581442(CHEMBL5086776)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581399BDBM50581399(CHEMBL5085226)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581400BDBM50581400(CHEMBL5075575)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237486BDBM50237486(CHEMBL4077433)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2019
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581426BDBM50581426(CHEMBL5089771)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581398BDBM50581398(CHEMBL5083519)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687847BDBM687847(US20240246981, Example 75)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687832BDBM687832(US20240246981, Example 60)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581450BDBM50581450(CHEMBL5085670)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687830BDBM687830(US20240246981, Example 58)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687846BDBM687846(US20240246981, Example 74)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652324BDBM652324(US20240059675, Example 26)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687833BDBM687833(US20240246981, Example 61)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652305BDBM652305(US20240059675, Example 8)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687834BDBM687834(US20240246981, Example 62)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652310BDBM652310(US20240059675, Example 13)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687822BDBM687822(US20240246981, Example 50)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687827BDBM687827(US20240246981, Example 55)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687843BDBM687843(US20240246981, Example 71)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687844BDBM687844(US20240246981, Example 72)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652312BDBM652312(US20240059675, Example 15)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652363BDBM652363(US20240059675, Example 32)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581412BDBM50581412(CHEMBL5088732)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687826BDBM687826(US20240246981, Example 54)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 762870BDBM762870(US20250250252, Example 1)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687858BDBM687858(US20240246981, Example 86)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519290BDBM50519290(CHEMBL4525926)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581445BDBM50581445(CHEMBL5089285)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581441BDBM50581441(CHEMBL5081653)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519285BDBM50519285(CHEMBL4445407)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581436BDBM50581436(CHEMBL5081891)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581443BDBM50581443(CHEMBL5083687)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581434BDBM50581434(CHEMBL5081537)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454733BDBM50454733(CHEMBL4204093)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human glutaminyl cyclase using Gln-AMC as substrate by pGAPase coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581451BDBM50581451(CHEMBL5092925)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 762871BDBM762871(US20250250252, Example 2)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652328BDBM652328(US20240059675, Example 30)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687808BDBM687808(US20240246981, Example 36)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652299BDBM652299(US20240059675, Example 3)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 762873BDBM762873(US20250250252, Example 4)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652309BDBM652309(US20240059675, Example 12)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687838BDBM687838(US20240246981, Example 66)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 762874BDBM762874(US20250250252, Example 5)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 762877BDBM762877(US20250250252, Example 8)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687842BDBM687842(US20240246981, Example 70)
Affinity DataIC50: 2nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612645BDBM50612645(CHEMBL5279792)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612631BDBM50612631(CHEMBL5266674)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
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