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Compile Data Set for Download or QSAR
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Found
24
of affinity data for UniProtKB/TrEMBL:
Q1HL33
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
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Affinity Data
Ki: 0.620nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
((R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |...)
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Affinity Data
Ki: 3.39nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
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Affinity Data
Ki: 7.76nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(CHEMBL16293 | Naphthalen | Naphthalin | naftaleno ...)
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Affinity Data
Ki: 9.33nM
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Target Info
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019729
((S)-5-(4,5-Dihydro-1H-imidazol-2-yl)-5,6,7,8-tetra...)
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Affinity Data
Ki: 9.77nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
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Affinity Data
Ki: 11.5nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
((4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro...)
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Affinity Data
Ki: 15.5nM
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 15.5nM
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
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Affinity Data
Ki: 17.0nM
More data for this Ligand-Target Pair
Target Info
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81984
(CAS_29110-47-2 | Guanfacine | NSC_3519)
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Affinity Data
Ki: 20.4nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
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Affinity Data
Ki: 24.0nM
More data for this Ligand-Target Pair
Target Info
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
Target Info
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PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Article
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 36.3nM
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Target Info
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
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Affinity Data
Ki: 40.7nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)
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Affinity Data
Ki: 43.6nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
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Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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Article
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM84342
(4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol...)
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Affinity Data
Ki: 389nM
More data for this Ligand-Target Pair
Target Info
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MCE
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PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85235
(CAS_4749-61-5 | ST 91 | ST-91)
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Affinity Data
Ki: 537nM
More data for this Ligand-Target Pair
Target Info
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50262235
(rilmenidine)
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Affinity Data
Ki: 724nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM35234
(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
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Affinity Data
Ki: 1.41E+3nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027069
((2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-ami...)
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Affinity Data
Ki: 2.40E+3nM
More data for this Ligand-Target Pair
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM25392
(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
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Affinity Data
Ki: >1.00E+4nM
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