Compile Data Set for Download or QSAR
Report error Found 124 of affinity data for UniProtKB/TrEMBL: Q7TQN8
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at rat GPR119 in GLUTag cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at rat GPR119 in golden hamster HIT-T15 cells assessed as induction of glucose-induced insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343443(tert-butyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343447(tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyra...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106208(CHEMBL3598101)
Affinity DataEC50:  11nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343452(tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyra...)
Affinity DataEC50:  15.5nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343445(tert-butyl 4-(3-(4-(methylsulfonyl)phenyl)isoxazol...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343446(tert-butyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  19.6nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343459(cyclopentyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyr...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  24nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by stead...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106161(CHEMBL3598092)
Affinity DataEC50:  28nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106206(CHEMBL3598099)
Affinity DataEC50:  29nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056104(CHEMBL3326689)
Affinity DataEC50:  31nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056010(CHEMBL3326673)
Affinity DataEC50:  31nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343442(isopropyl 4-(1-(2-fluoro-4-(methylsulfonyl)phenyl)...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343458(isopropyl 4-(3-(4-(methylsulfonyl)phenyl)isoxazolo...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056055(CHEMBL3326688)
Affinity DataEC50:  41nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056009(CHEMBL3326672)
Affinity DataEC50:  41nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343460(tert-butyl 4-(3-methyl-1-(4-(methylsulfonyl)phenyl...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343454(tert-butyl 4-(3-(4-(methylsulfonyl)phenyl)-3H-[1,2...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106154(CHEMBL3598085)
Affinity DataEC50:  45nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50055996(CHEMBL3325846)
Affinity DataEC50:  47nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056105(CHEMBL3326678)
Affinity DataEC50:  49nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106207(CHEMBL3598100)
Affinity DataEC50:  50nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50055994(CHEMBL3325844)
Affinity DataEC50:  50nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343450(ethyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106160(CHEMBL3598091)
Affinity DataEC50:  54nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataEC50:  55nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106125(CHEMBL3598113)
Affinity DataEC50:  60nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106152(CHEMBL3598083)
Affinity DataEC50:  61nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056007(CHEMBL3326670)
Affinity DataEC50:  63nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106159(CHEMBL3598090)
Affinity DataEC50:  64nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343456(neopentyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyraz...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106126(CHEMBL3598114)
Affinity DataEC50:  65nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106211(CHEMBL3598104)
Affinity DataEC50:  67nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056018(CHEMBL3326681)
Affinity DataEC50:  69nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106210(CHEMBL3598103)
Affinity DataEC50:  72nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056013(CHEMBL3326676)
Affinity DataEC50:  77nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106216(CHEMBL3598109)
Affinity DataEC50:  80nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343448(tert-butyl 4-((1-(2-fluoro-4-(methylsulfonyl)pheny...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at rat GPR119 by melanophore assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106157(CHEMBL3598088)
Affinity DataEC50:  89nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106150(CHEMBL3598081)
Affinity DataEC50:  94nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106124(CHEMBL3598112)
Affinity DataEC50:  98nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106217(CHEMBL3598110)
Affinity DataEC50:  101nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056033(CHEMBL3326686)
Affinity DataEC50:  103nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50106212(CHEMBL3598105)
Affinity DataEC50:  108nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056003(CHEMBL3326666)
Affinity DataEC50:  109nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056002(CHEMBL3325852)
Affinity DataEC50:  110nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
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