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Report error Found 4 of affinity data for UniProtKB/TrEMBL: Q8BTW9
TargetSerine/threonine-protein kinase PAK 4(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataEC50:  4nMAssay Description:Inhibition of PAK4 in mouse NIH3T3 cells assessed as reduction in phosphorylated GEF-H1 accumulation incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PAK 4(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)
Affinity DataEC50:  13nMAssay Description:Inhibition of PAK4 in mouse NIH3T3 cells assessed as reduction in phosphorylated GEF-H1 accumulation incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PAK 4(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)
Affinity DataEC50:  32nMAssay Description:Inhibition of PAK4 in mouse NIH3T3 cells assessed as reduction in phosphorylated GEF-H1 accumulation incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PAK 4(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50389109(CHEMBL2064557)
Affinity DataEC50:  810nMAssay Description:Inhibition of PAK4 in mouse NIH3T3 cells assessed as reduction in phosphorylated GEF-H1 accumulation incubated for 30 mins by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)