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Report error Found 11 of affinity data for UniProtKB/TrEMBL: Q8DQ16
TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.0 T: 22°CAssay Description:Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM22112(7-({3-[(methylsulfanyl)methyl]azetidin-1-yl}methyl...)
Affinity DataKi:  84nM ΔG°:  -40.0kJ/molepH: 7.0 T: 22°CAssay Description:Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM22110(Azetidine based compound, 43 | [1-({4-amino-5H-pyr...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.0 T: 22°CAssay Description:Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36435((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...)
Affinity DataKd:  10nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36495(CHEMBL554642 | ImmA-Bn)
Affinity DataKd:  210nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36496(CHEMBL552894 | ImmA-pClPh)
Affinity DataKd:  190nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.360nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36497(CHEMBL191436 | DADMe-ImmA-Bn)
Affinity DataKd:  2.40nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKd:  24nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM50170093(2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-3,4-di...)
Affinity DataKd:  1.00E+3nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Industrial Research

LigandPNGBDBM36494(CHEMBL554965 | ImmA-Et)
Affinity DataKd:  40nMpH: 7.5 T: 25°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed