Compile Data Set for Download or QSAR
Report error Found 22 of affinity data for UniProtKB/TrEMBL: Q8JUX6
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647020BDBM50647020(CHEMBL5594644)
Affinity DataIC50: 60nMAssay Description:Inhibition of 6his-tagged N/C-terminal CHIKV nsP2 (1009 to 1329 residues) extracted from Escherichia coli Rosetta2 (DE3) cells preincubated with comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274328BDBM50274328(CHEMBL6074586)
Affinity DataIC50: 109nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274330BDBM50274330(CHEMBL6078085)
Affinity DataIC50: 114nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274329BDBM50274329(CHEMBL6103017)
Affinity DataIC50: 118nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668244BDBM50668244(CHEMBL6193347)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal 6-His/SUMO-tagged CHIKV 181/25 nsP2 extracted from Escherichia coli Rosetta 2 assessed as decrease in nsP2 helicase activity...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650313BDBM50650313(CHEMBL5630381)
Affinity DataIC50: 950nMAssay Description:Inhibition of CHIKV nsP2 protease activity assessed as decrease in the fluorescence signal using peptide substrate measured for 20 mins by FRET analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650313BDBM50650313(CHEMBL5630381)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to CHIKV nsP2 assessed as inhibition constant by measuring fluorescence by multimode microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450958BDBM50450958(CHEMBL4209509)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of Chikungunya virus nsP2 protease infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450957BDBM50450957(CHEMBL3125915)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of Chikungunya virus nsP2 protease infected in African green monkey Vero cells assessed as inhibition of viral-induced cytopathic effect b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650311BDBM50650311(CHEMBL5630521)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of CHIKV nsP2 protease activity assessed as decrease in the fluorescence signal using peptide substrate measured for 20 mins by FRET analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650314BDBM50650314(CHEMBL5629997)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of CHIKV nsP2 protease activity assessed as decrease in the fluorescence signal using peptide substrate measured for 20 mins by FRET analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650312BDBM50650312(CHEMBL5624692)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CHIKV nsP2 protease activity assessed as decrease in the fluorescence signal using peptide substrate measured for 20 mins by FRET analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650311BDBM50650311(CHEMBL5630521)
Affinity DataKi:  4.86E+4nMAssay Description:Binding affinity to CHIKV nsP2 assessed as inhibition constant by measuring fluorescence by multimode microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650312BDBM50650312(CHEMBL5624692)
Affinity DataKi:  9.23E+4nMAssay Description:Binding affinity to CHIKV nsP2 assessed as inhibition constant by measuring fluorescence by multimode microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650311BDBM50650311(CHEMBL5630521)
Affinity DataKd:  1.27E+5nMAssay Description:Binding affinity to CHIKV nsP2 assessed as equilibrium dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650312BDBM50650312(CHEMBL5624692)
Affinity DataKd:  1.59E+5nMAssay Description:Binding affinity to CHIKV nsP2 assessed as equilibrium dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650314BDBM50650314(CHEMBL5629997)
Affinity DataKi:  1.82E+5nMAssay Description:Binding affinity to CHIKV nsP2 assessed as inhibition constant by measuring fluorescence by multimode microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650313BDBM50650313(CHEMBL5630381)
Affinity DataKd:  1.98E+5nMAssay Description:Binding affinity to CHIKV nsP2 assessed as equilibrium dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650314BDBM50650314(CHEMBL5629997)
Affinity DataKd:  2.18E+5nMAssay Description:Binding affinity to CHIKV nsP2 assessed as equilibrium dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668300BDBM50668300(CHEMBL5396687)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of CHIKV nsP2 protease by FRET assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668301BDBM50668301(CHEMBL6188813)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of CHIKV nsP2 protease by FRET assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyprotein P1234(CHIKV)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420456BDBM50420456(CHEMBL1605548)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of CHIKV nsP2 protease by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed