Compile Data Set for Download or QSAR
Report error Found 7 of affinity data for UniProtKB/TrEMBL: Q8NFT8
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 142nMAssay Description:Inhibition of BET in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 196nMAssay Description:Inhibition of BET in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 310nMAssay Description:Inhibition of BET in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 458nMAssay Description:Inhibition of BET in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 647nMAssay Description:Inhibition of BET in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell proliferat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDelta and Notch-like epidermal growth factor-related receptor(Human)
Knight Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527598(CHEMBL4303293)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of BET in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed