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Report error Found 101 of affinity data for UniProtKB/TrEMBL: Q8WTQ7
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  0.860nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human GRK7 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human GRK7 using casein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GRK7 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50566949(CHEMBL4877302)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  7.20nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50566946(CHEMBL4854871)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50566947(CHEMBL4847703)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  48nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  48nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50242737((R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimet...)
Affinity DataKd:  61nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  180nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  180nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 180nMAssay Description:Inhibition of GRK7-mediated bovine tubulin phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  310nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  360nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25013(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...)
Affinity DataKd:  380nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  470nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataKd:  540nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd:  540nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd:  550nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd:  820nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd:  850nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  980nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GRK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GRK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50257340(CHEMBL4072828)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd:  4.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  5.00E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataKd:  7.50E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50257328(CHEMBL4082775)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2019
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50: 9.14E+3nMAssay Description:Inhibition of human GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50554258(CHEMBL4744858)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetRhodopsin kinase GRK7(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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