Compile Data Set for Download or QSAR
Report error Found 70 of affinity data for UniProtKB/TrEMBL: Q96JD6
Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269341BDBM269341((R)-2-(4-(6-fluoronaphthalen-2-yl)-2-methylphenyl)...)
Affinity DataIC50: 25.1nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269329BDBM269329((R)-2-(3-fluoro-4'-(1-methyl-1H-pyrazol-4-yl)-[1,1...)
Affinity DataIC50: 41.7nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269323BDBM269323((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 47.9nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269337BDBM269337(2-(4-(6-fluoronaphthalen-2-yl)-2-methylphenyl)-4,4...)
Affinity DataIC50: 50.1nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269321BDBM269321((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 52.5nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269322BDBM269322((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269339BDBM269339((R)-4,4-dimethyl-2-(3-methyl-4'-(1-methyl-1H-pyraz...)
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50119581BDBM50119581(CHEMBL3617742 | US9718813, Compound 23 | US1041354...)
Affinity DataIC50: 56.2nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269327BDBM269327(2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-4,4...)
Affinity DataIC50: 58.9nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269304BDBM269304((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 63.1nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269328BDBM269328((R)-2-(2-fluoro-4-(1-methyl-1H-indazol-5-yl)phenyl...)
Affinity DataIC50: 67.6nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269285BDBM269285((R)-1((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)met...)
Affinity DataIC50: 67.6nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269283BDBM269283((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 72.4nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269296BDBM269296((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 74.1nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269342BDBM269342(4,4-dimethyl-2-(3-methyl-4'-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 87.1nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269325BDBM269325(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 107nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269335BDBM269335((R)-4,4-dimethyl-2-(2-methyl-4-(1-methyl-1H-indazo...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269300BDBM269300((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 112nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269334BDBM269334(2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-1-(...)
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269301BDBM269301((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 126nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 268885BDBM268885((4RS)-2-(4-(1H-Indol-5-yl)phenyl)-1-(((R)-1-(cyclo...)
Affinity DataIC50: 129nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50119580BDBM50119580(CHEMBL3617741 | US9718813, Compound 1 | US10413545...)
Affinity DataIC50: 138nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269294BDBM269294(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 155nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269340BDBM269340((R)-4,4-dimethyl-2-(2-methyl-4-(1-methyl-1H-benzo[...)
Affinity DataIC50: 158nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269338BDBM269338(4,4-dimethyl-2-(2-methyl-4-(1-methyl-1H-benzo[d]im...)
Affinity DataIC50: 174nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269270BDBM269270((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 178nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269318BDBM269318((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 186nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269287BDBM269287(US9718813, Compound 69 | 1-((1-(cyclopropanecarbon...)
Affinity DataIC50: 214nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269299BDBM269299((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 224nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269284BDBM269284(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269310BDBM269310(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 251nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269277BDBM269277(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 269nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269309BDBM269309(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 282nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269302BDBM269302((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 302nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50119583BDBM50119583(CHEMBL3617744 | US9718813, Compound 53 | US1041354...)
Affinity DataIC50: 324nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50119582BDBM50119582(CHEMBL3617743 | US9718813, Compound 40 | US1041354...)
Affinity DataIC50: 347nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269305BDBM269305((R)-2-(4-(benzo[d]thiazol-2-yl)-2-fluorophenyl)-1-...)
Affinity DataIC50: 355nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269279BDBM269279(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 355nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269332BDBM269332(4,4-dimethyl-2-(2-methyl-4-(1-methyl-1H-indazol-5-...)
Affinity DataIC50: 363nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269076BDBM269076((4RS)-2-(4-(Benzofuran-5-yl)phenyl)-1-(((R)-1-(cyc...)
Affinity DataIC50: 389nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269282BDBM269282(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 389nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269288BDBM269288(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 417nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 268883BDBM268883((4RS)-1-(((R)-1-(cyclopropanecarbonyl)pyrrolidin-3...)
Affinity DataIC50: 417nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269306BDBM269306((R)-2-(4-(benzo[d]oxazol-2-yl)-2-fluorophenyl)-1-(...)
Affinity DataIC50: 437nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269286BDBM269286((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 468nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 268661BDBM268661((R)-2-(4-(benzofuran-5-yl)phenyl)-1-((1-(cycloprop...)
Affinity DataIC50: 468nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269311BDBM269311(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 468nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269297BDBM269297((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 479nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 268738BDBM268738((4RS)-2-(4-(Benzofuran-5-yl)phenyl)-1-(((R)-1-(cyc...)
Affinity DataIC50: 537nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

Target1,5-anhydro-D-fructose reductase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 269317BDBM269317(1-((1-(cyclopropanecarbonyl)azetidin-3-yl)methyl)-...)
Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

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