Compile Data Set for Download or QSAR
Report error Found 28 of affinity data for UniProtKB/TrEMBL: Q9R1U7
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420231BDBM50420231(CHEMBL2074600)
Affinity DataKi:  3.09E+3nMAssay Description:TP_TRANSPORTER: inhibition of Pravastatin uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataKi:  4.43E+3nMAssay Description:TP_TRANSPORTER: inhibition of PCG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataIC50: 6.03E+3nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366524BDBM50366524(Estrone Sulphate | ESTRONE | ESTROPIPATE | Estrone...)
Affinity DataKi:  9.10E+3nMAssay Description:TP_TRANSPORTER: inhibition of PCG uptake in OAT3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20688BDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)
Affinity DataIC50: 1.56E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009999BDBM50009999(CHEMBL461 | N-benzoylglycine)
Affinity DataKi:  1.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of benzylpenicillin uptake in Oat3-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206509BDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataKi:  2.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344959BDBM50344959(17beta-Estradiol-17-(beta-D-glucuronide) | estradi...)
Affinity DataKi:  3.56E+4nMAssay Description:TP_TRANSPORTER: inhibition of PCG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103595BDBM50103595(CHEBI:3699 | Brumetadina | Cimetidine | Tagamet | ...)
Affinity DataKi:  4.68E+4nMAssay Description:TP_TRANSPORTER: inhibition of PCG uptake in OAT3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344964BDBM50344964(Betamipron | N-(phenylcarbonyl)-beta-alanine | CHE...)
Affinity DataIC50: 4.75E+4nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82898BDBM82898(SMR000386987 | MLS001048966 | (6R,7R)-3-(acetyloxy...)
Affinity DataKi:  4.80E+4nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022787BDBM50022787((+)-3,3-Dimethyl-7-oxo-6-phenylacetylamino-4-thia-...)
Affinity DataKi:  5.28E+4nMAssay Description:TP_TRANSPORTER: inhibition of Pravastatin uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350468BDBM50350468(CEFAMANDOLE)
Affinity DataIC50: 9.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22889BDBM22889(N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfa...)
Affinity DataIC50: 1.66E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270006BDBM50270006(2-(4-aminobenzamido)acetate | AMINOHIPPURATE)
Affinity DataKi:  3.01E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240008BDBM50240008(CHEBI:104011 | Aminohippuric Acid | PAHA | Para-Am...)
Affinity DataKi:  3.98E+5nMAssay Description:TP_TRANSPORTER: inhibition of PCG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420240BDBM50420240(CHEMBL2074590)
Affinity DataKi:  5.82E+5nMAssay Description:TP_TRANSPORTER: inhibition of benzylpenicillin uptake in Oat3-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139896BDBM50139896((6R,7R)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-met...)
Affinity DataIC50: 6.30E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390999BDBM50390999(CEFOPERAZONE)
Affinity DataKi:  6.70E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367502BDBM50367502(CILASTATIN)
Affinity DataIC50: 7.42E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370587BDBM50370587(CEFAZOLIN)
Affinity DataKi:  7.80E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375594BDBM50375594(TAUROCHOLATE)
Affinity DataKi:  7.90E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50482777BDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 8.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103624BDBM50103624(CHEBI:3537 | 40602 | Cefaloridine | Cephaloridine ...)
Affinity DataKi:  1.14E+6nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270006BDBM50270006(2-(4-aminobenzamido)acetate | AMINOHIPPURATE)
Affinity DataKi:  1.35E+6nMAssay Description:TP_TRANSPORTER: inhibition of Pravastatin uptake in Oat3-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350467BDBM50350467(BL-S578 | Cefadrops | CEFADROXIL)
Affinity DataIC50: 1.78E+6nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350467BDBM50350467(BL-S578 | Cefadrops | CEFADROXIL)
Affinity DataIC50: 1.78E+6nMAssay Description:Inhibition of rat OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103601BDBM50103601(CHEBI:29007 | Ceftriaxone)
Affinity DataIC50: 2.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed