15 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.
National Human Genome Research Institute
Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1a inhibitors.
National Human Genome Research Institute
Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
National Human Genome Research Institute
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.
National Human Genome Research Institute
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
National Human Genome Research Institute
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
National Human Genome Research Institute
Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
National Human Genome Research Institute
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease.
National Human Genome Research Institute
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk).
National Human Genome Research Institute
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
National Human Genome Research Institute
Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550).
National Human Genome Research Institute
Non-iminosugar glucocerebrosidase small molecule chaperones.
National Human Genome Research Institute
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.
National Human Genome Research Institute
Characterization of chemical libraries for luciferase inhibitory activity.
National Human Genome Research Institute
