PMID

Data

Article Title

Organization

Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes.

Merck Research Laboratories

The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors.

Merck Research Laboratories

New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation.

Katholieke Universiteit Leuven

New derivatives of kanamycin B obtained by modifications and substitutions in position 6''. 2. In vitro and computer-aided toxicological evaluation with respect to interactions with phosphatidylinositol.

Universit£

Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling.

Groningen Research Institute of Pharmacy

Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with ?-ketoamide warheads.

The Czech Academy of Sciences

Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor.

Sungkyunkwan University

Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2.

Ku Leuven

A cell-based fluorescent assay for FAP inhibitor discovery.

Peking University First Hospital

Scaffold-hopping from xanthines to tricyclic guanines: A case study of dipeptidyl peptidase 4 (DPP4) inhibitors.

Merck Research Laboratories

Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein ?.

Mcgill University

Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation.

University of Michigan