Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

Advanced Search

48 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF

Radionetics Oncology

Pyrimidine Heterocyclic Compound, Preparation Method Thereof and use Thereof in Medicine

Insilico Medicine IP

Pyrazolopyridinone Compounds

Beigene

NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF

Applied Pharmaceutical Science

AMINOHETEROARYL KINASE INHIBITORS

Anrui Biomedical Technology (Guangzhou) Co.

N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS

Mission Therapeutics

SARS-CoV-2 inhibitors for treating coronavirus infections

Insilico Medicine Ip

Pyridone amides as modulators of sodium channels

Vertex Pharmaceuticals

Sting modulator compounds, and methods of making and using

Takeda Pharmaceutical

Compounds for inhibiting TNIK and medical uses thereof

Korea Research Institute of Chemical Technology

CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer

Amgen

Combination therapy for treatment of hematological diseases

Incyte

Substituted carboxamides as inhibitors of WDR5 protein-protein binding

Propellon Therapeutics

Compositions and methods for treating KIT- and PDGFRA-mediated diseases

Blueprint Medicines

Iso-citrate dehydrogenase (IDH) inhibitor

Shanghai Meton Pharmaceutical

Indole derivatives and their use in neurodegenerative diseases

Merck Patent

Pharmacokinetically improved compounds

Surface Logix

Heterocyclic sulfonamide derivative and medicine containing same

Ea Pharma

TYK2 inhibitors and uses thereof

Nimbus Lakshimi

Isoquinolin-3-YL carboxamides and preparation and use thereof

Samumed

SGC stimulators

Ironwood Pharmaceuticals

Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors

Incyte

Polymorphs of N-[(R)-1-[(S)-1-(4-aminomethyl-benzylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(4-ethoxy-phenyl)-ethyl]-benzamide hydrochloride

Kalvista Pharmaceuticals

Carbonic anhydrase inhibitors: in vitro inhibition of a isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids.

Ondokuz Mayis University

Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors

Vtv Therapeutics

Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use

Merck Sharp & Dohme

Monocyclic heteroaryl cycloalkyldiamine derivatives

Novartis

Selective NR2B antagonists

Bristol-Myers Squibb

Quinoline derivatives as PDE10A enzyme inhibitors

H. Lundbeck

Discovery of isoalloxazine derivatives as a new class of potential anti-Alzheimer agents and their synthesis.

The M. S. University of Baroda

Bicyclic compound or salt thereof

Taiho Pharmaceutical

Aminopyrazole derivative

Chugai Seiyaku Kabushiki Kaisha

Substituted spiro[cycloalkyl-1,3′-indo]-2′(1′H)-one derivatives and their use as P38 mitogen-activated kinase inhibitors

Almirall

1,4-oxazepines as BACE1 and/or BACE2 inhibitors

Hoffmann-La Roche

Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

Methylgene

Monoamine oxidase inhibition by C4-substituted phthalonitriles.

North-West University

Pharmacological characterization of a novel nonpeptide antagonist radioligand, (+/-)-N-[2-methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for corticotropin-releasing factor1 receptors.

Bristol-Myers Squibb Pharmaceuticals Research Institute

Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior.

Bayer

Characterization of 5-hydroxytryptamine1B receptors in rat spinal cord via [125I]iodocyanopindolol binding and inhibition of [3H]-5-hydroxytryptamine release.

University of Texas

A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".

Griffith University

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.

Universitat De Barcelona

Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities.

Hong Kong University of Science and Technology

Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity.

Weizmann Institute of Science