23 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Anti-inflammatory tetraquinane diterpenoids from a Crinipellis species.
University of Kaiserslautern
Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.
University of Pittsburgh
2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.
University of Pittsburgh
Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species.
Institute of Biotechnology and Drug Research (Ibwf)
Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.
University of Salerno
Inhibiting aberrant signal transducer and activator of transcription protein activation with tetrapodal, small molecule Src homology 2 domain binders: promising agents against multiple myeloma.
University of Toronto Mississauga
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
University of Southern California
Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity.
University of Toronto
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.
Fudan University
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.
University of Michigan
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein.
TBA
A small-molecule screen identifies the antitrypanosomal agent suramin and analogues NF023 and NF449 as inhibitors of STAT5a/b.
Leipzig University
6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity
University of Pittsburgh
6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-B][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity
University of Pittsburgh
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
University of Central Florida College of Medicine
An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.
University of Central Florida College of Medicine