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32 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

Article Title
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARa Selective Agonist.EBI
Bristol-Myers Squibb
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) Agonist.EBI
Vitae Pharmaceuticals
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligandsEBI
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analoguesEBI
Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostereEBI
Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acidsEBI
Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity.EBI
Okayama University Graduate School Of Medicine
Aza-retinoids as novel retinoid X receptor-specific agonists.EBI
Ligand Pharmaceuticals
Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.EBI
Goethe-University Frankfurt
Design, synthesis and structure-activity relationship of novel RXR-selective modulators.EBI
Ligand Pharmaceuticals
Design and synthesis of novel RXR-selective modulators with improved pharmacological profile.EBI
Ligand Pharmaceuticals
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid.EBI
Ligand Pharmaceuticals
An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.EBI
The Ohio State University
Enantioselective syntheses of potent retinoid X receptor ligands: differential biological activities of individual antipodes.EBI
Discovery of Second Generation ROR? Inhibitors Composed of an Azole Scaffold.EBI
Kyoto Prefectural University Of Medicine
Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).EBI
Arizona State University
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.EBI
Goethe University Frankfurt
Structure-activity relationship studies of novel heteroretinoids: induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid.EBI
Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands.EBI
Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells.EBI
Ligand Pharmaceuticals
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype.EBI
Goethe-University Frankfurt
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.EBI
University Of Tokyo
Discovery of potent and selective PPAR?/? dual antagonists and initial biological studies.EBI
Inception Sciences
Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid.EBI
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.EBI
Goethe-University Frankfurt
Identification of the first retinoid X, receptor homodimer antagonist.EBI
Ligand Pharmaceuticals
Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells.EBI
Ligand Pharmaceuticals
Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.EBI
Ligand Pharmaceuticals
Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids.EBI
Tohoku Pharmaceutical University
Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity.EBI
Sri International
Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics.EBI
Swiss Federal Institute Of Technology (Eth)
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.EBI
St. John'S University