32 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARa Selective Agonist.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Bristol-Myers Squibb
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR)ß Agonist.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Vitae Pharmaceuticals
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analogues![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostere![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acids![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
TBA
Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Okayama University Graduate School of Medicine
Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Goethe-University Frankfurt
Design, synthesis and structure-activity relationship of novel RXR-selective modulators.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Design and synthesis of novel RXR-selective modulators with improved pharmacological profile.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
The Ohio State University
Enantioselective syntheses of potent retinoid X receptor ligands: differential biological activities of individual antipodes.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Allergan
Discovery of Second Generation ROR? Inhibitors Composed of an Azole Scaffold.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Kyoto Prefectural University of Medicine
Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Arizona State University
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Goethe University Frankfurt
Structure-activity relationship studies of novel heteroretinoids: induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Università
Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Allergan
Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Goethe-University Frankfurt
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
University of Tokyo
Discovery of potent and selective PPAR?/? dual antagonists and initial biological studies.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Inception Sciences
Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Allergan
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Goethe-University Frankfurt
Identification of the first retinoid X, receptor homodimer antagonist.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Ligand Pharmaceuticals
Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Tohoku Pharmaceutical University
Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Sri International
Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics.![EBI](/images/logo_chembl.png)
![EBI](/images/logo_chembl.png)
Swiss Federal Institute of Technology (Eth)