BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.3M Compounds and 9.3K Targets. Of those, 1,372K data for 638K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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7 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors.EBI
Vertex Pharmaceuticals
Design and synthesis of Rho kinase inhibitors (II).EBI
Kirin Brewery
Design and synthesis of rho kinase inhibitors (III).EBI
Kirin Brewery
Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase C? (PKC?) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis.EBI
Vertex Pharmaceuticals
The Rise of Molecules Able To Regenerate the Central Nervous System.EBI
Universit£
Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors.EBI
Purdue University
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.EBI
Abbvie Bioresearch Center