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BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 765K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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18 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
305
Compounds and compositions as RAF kinase inhibitorsBDB
Novartis
12
Opioid agonists and uses thereofBDB
Nektar Therapeutics
85
Thiazoles as modulators of RORγtBDB
Janssen Pharmaceutica
91
Keto-imidazopyridine derivatives as RORc modulatorsBDB
Genentech
431
2-(morpholin-4-yl)-1,7-naphthyridinesBDB
Bayer
20
Selective glycosidase inhibitors and uses thereofBDB
Alectos Therapeutics
483
BTK InhibitorsBDB
Merck Sharp & Dohme
48
Macrocyclic compounds as Trk kinase inhibitorsBDB
Array Biopharma
86
Substituted aza-bicyclic imidazole derivatives useful TRPM8 receptor modulatorsBDB
Janssen Pharmaceutica
181
Non-nucleoside reverse transcriptase inhibitorsBDB
Merck Sharp & Dohme
15
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.BDB
Abbott Laboratories
17
Structure-based design of caspase-1 inhibitor containing a diphenyl ether sulfonamide.BDB
Pfizer
32
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.BDB
Novartis Pharmaceuticals
33
Tyrosine kinase inhibitors. 18. 6-Substituted 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as soluble, irreversible inhibitors of the epidermal growth factor receptor.BDB
University of Auckland
16
2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors.BDB
Merck Sharp and Dohme Research Laboratories
47
Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390: a lead HIV protease inhibitor.BDB
Parke-Davis Pharmaceutical Research
47
Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.BDB
Eli Lilly
30
Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679.BDB
Merck Sharp and Dohme Research Laboratories