36 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
4
Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability.
Shenyang Pharmaceutical University
34
Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety.
Nagoya City University
44
A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1.
The Ohio State University
18
Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.
Pfizer
15
Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors.
Shenyang Pharmaceutical University
12
Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.
Peking Union Medical College
2
Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.
The University of Western Ontario
18
Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors.
Peking Union Medical College
25
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.
Vernalis (R&D)
40
Structure-Guided Optimization and Preclinical Evaluation of 6-O-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.
Sichuan University
32
Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors.
Chinese Academy of Medical Sciences and Peking Union Medical College
49
Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs.
Sichuan Kelun-Biotech Biopharmaceutical
47
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions.
Shanghai University
31
Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.
University of Michigan
19
Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries.
Max Planck Research Unit For Enzymology of Protein Folding
25
Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides.
Cnrs-University of Lille 2 Umr 8525
6
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins.
Chinese Academy of Sciences
17
Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).
Chinese Academy of Sciences
9
Targeting Protein Folding: A Novel Approach for the Treatment of Pathogenic Bacteria.
University of W£Rzburg
4
A Phosphoramidate Strategy Enables Membrane Permeability of a Non-nucleotide Inhibitor of the Prolyl Isomerase Pin1.
University of California San Francisco
25
Synthesis and Pin1 inhibitory activity of thiazole derivatives.
Peking Union Medical College
56
Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.
Peking Union Medical College
10
Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties.
Max-Planck Research Unit
24
Design, synthesis and biological evaluation of benzimidazole derivatives as novel human Pin1 inhibitors.
Shenyang Pharmaceutical University
5
An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity.
Nagoya Citi University
2
Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
Sichuan University
11
Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.
The Ohio State University
11
Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity.
Shenyang Pharmaceutical University
47
Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.
Peking Union Medical College
17
Conjugates of 18β-glycyrrhetinic acid derivatives with 3-(1H-benzo[d]imidazol-2-yl)propanoic acid as Pin1 inhibitors displaying anti-prostate cancer ability.
Shenyang Pharmaceutical University
41
Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition containing the same, preparation method and use thereof
Shanghai Huilun Life Science & Technology