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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745517([1-(3-fluoro-4-methoxyphenyl)- 1,4,6,7-tetrahydrop...)
Affinity DataEC50:  730nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.45E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745530([1-[3-chloro-4- (difluoromethoxy)phenyl]-1,4,5,6- ...)
Affinity DataEC50:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50634562(CHEMBL5431661 | US20250171467, Compound 27)
Affinity DataEC50:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745528([1-(3-chlorophenyl)-1,4,5,6- tetrahydrocyclopenta[...)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745527([1-(3-chloro-4-fluorophenyl)- 1,4,5,6- tetrahydroc...)
Affinity DataEC50:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50634561(CHEMBL5426863 | US20250171467, Compound 24)
Affinity DataEC50:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745525([S or R]-(6,6-difluoro-1,4- diazabicyclo[3.2.2]non...)
Affinity DataEC50:  66nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745524([R or S]-(6,6-difluoro-1,4- diazabicyclo[3.2.2]non...)
Affinity DataEC50:  16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745503(US20250171467, Compound 21)
Affinity DataEC50:  0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50634559(CHEMBL5420341 | US20250171467, Compound 20)
Affinity DataEC50:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50634558(CHEMBL5398714 | US20250171467, Compound 19)
Affinity DataEC50:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50634557(CHEMBL5406074 | US20250171467, Compound 18)
Affinity DataEC50:  0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745519(1,4-diazabicyclo[3.2.2]nonan-4-yl- [1-(4-methoxyph...)
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745518([1-(3-chloro-4-methoxyphenyl)- 1,4,6,7-tetrahydrop...)
Affinity DataEC50:  2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50406123(CHEMBL5277419 | US20250171467, Compound 1)
Affinity DataEC50:  8.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745516([1-[4-methoxy-3- (trifluoromethyl)phenyl]-1,4,6,7-...)
Affinity DataEC50:  320nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745515(Racemic-(6-fluoro-1,4-diazepan-1- yl)-[1-(4-methox...)
Affinity DataEC50:  2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745514(Racemic-3,9- diazabicyclo[4.2.1 ]nonan-3-yl-[1- (4...)
Affinity DataEC50:  840nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745513([4-(2-fluoroethyl)-1,4-diazepan-1- yl]-[1-(4-metho...)
Affinity DataEC50:  1.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745512(Racemic-1,4- diazabicyclo[3.2.1]octan-4-yl-[1-(4- ...)
Affinity DataEC50:  180nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50406119(CHEMBL5273405 | US20250171467, Compound 9)
Affinity DataEC50:  120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745510(5,8-diazaspiro[2.6]nonan-8-yl-[1- (4-methoxyphenyl...)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745509(Racemic-[1-(4-methoxyphenyl)- 1,4,6,7-tetrahydropy...)
Affinity DataEC50:  250nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745508(US20250171467, Compound 6)
Affinity DataEC50:  360nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745507(1,4-diazabicyclo[3.2.2]nonan-4-yl- [1-[4-(difluoro...)
Affinity DataEC50:  29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50406128(CHEMBL5270537 | US20250171467, Compound 4)
Affinity DataEC50:  940nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745505(US20250171467, Compound 3)
Affinity DataEC50:  1.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745504(US20250171467, Compound 2)
Affinity DataEC50:  7.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent