BDBM50131053 10-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::10-Methoxylrutaecarpine::CHEMBL85826::cid_378227
SMILES COc1ccc2[nH]c-3c(CCn4c-3nc3ccccc3c4=O)c2c1
InChI Key InChIKey=JNHSRGXMKPJTEV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50131053
Affinity DataIC50: 1.72E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >5.57E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
Affinity DataEC50: 185nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: <2.83nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of human CYP1B1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of human Cytochrome P450 1B1 expressed in bacterial membraneMore data for this Ligand-Target Pair
TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human CYP1A1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3 [702-738,740-752](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: >1.86E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair