BDBM50131040 3-Chloro-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::3-Chlororutaecarpine::CHEMBL85106

SMILES Clc1ccc2nc3-c4[nH]c5ccccc5c4CCn3c(=O)c2c1

InChI Key InChIKey=PXJKYEMXHIFINY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131040   

TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131040(3-Chloro-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2...)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131040(3-Chloro-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131040(3-Chloro-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2...)
Affinity DataIC50:  29nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed