BDBM50113835 4-Fluoro-benzylamine::4-fluorobenzylamine::CHEMBL12392::Integrase inhibitor, R1{2}

SMILES NCc1ccc(F)cc1

InChI Key InChIKey=IIFVWLUQBAIPMJ-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50113835   

TargetSerine protease 1(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50113835(4-Fluoro-benzylamine | 4-fluorobenzylamine | CHEMB...)
Affinity DataKi:  430nMAssay Description:Binding affinity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50113835(4-Fluoro-benzylamine | 4-fluorobenzylamine | CHEMB...)
Affinity DataKd:  4.27E+5nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50113835(4-Fluoro-benzylamine | 4-fluorobenzylamine | CHEMB...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Bristol-Myers Squibb

LigandPNGBDBM50113835(4-Fluoro-benzylamine | 4-fluorobenzylamine | CHEMB...)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition assay using HIV-1 integrase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50113835(4-Fluoro-benzylamine | 4-fluorobenzylamine | CHEMB...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed