BDBM50339586 2-(4-hydroxyphenyl)acetic acid::4-HYDROXYPHENYLACETATE::4-Hydroxyphenylacetic acid::CHEMBL1772

SMILES OC(=O)Cc1ccc(O)cc1

InChI Key InChIKey=XQXPVVBIMDBYFF-UHFFFAOYSA-N

Data  8 KI  1 EC50

PDB links: 11 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50339586   

TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  900nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of [3H]NCS-382 binding to CaMK2alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataKi:  3.09E+5nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOlfactory receptor class A-like protein 1(Danio rerio (Zebrafish))
German Institute Of Human Nutrition Potsdam-Rehbruecke

LigandPNGBDBM50339586(2-(4-hydroxyphenyl)acetic acid | 4-HYDROXYPHENYLAC...)
Affinity DataEC50:  1.90E+3nMpH: 7.4Assay Description:Briefly, HEK 293T cells stably expressing the G protein-chimera Gα16gust44 were seeded onto 96-well plates coated with 10 μg/ml of poly-D-l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed