BDBM50340330 7-azamelatonin::CHEMBL137969::N-[2-(5-Methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-ethyl]-acetamide

SMILES COc1cnc2[nH]cc(CCNC(C)=O)c2c1

InChI Key InChIKey=COGBYVKHQGKYBA-UHFFFAOYSA-N

Data  4 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50340330   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataKi:  40nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]2-Iodomelatonin from human MT1 receptor expressed in HEK293 cells after 120 mins by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataKi:  117nMAssay Description:Displacement of [125I]2-Iodomelatonin from human MT2 receptor expressed in HEK293 cells after 120 mins by radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataKi:  117nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340330(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Affinity DataIC50:  126nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed