BDBM50276826 (1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-xyphenoxy)-2,4,9-trihydroxydibenzo-1,4-dioxin)::7-Phloroethol::CHEMBL456228

SMILES Oc1cc(O)c(Oc2cc(O)c3Oc4c(Oc5cc(O)cc(O)c5)c(O)cc(O)c4Oc3c2)c(O)c1

InChI Key InChIKey=JLEVVQRBEATTCM-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50276826   

TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataKi:  7.20E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataKi:  1.93E+4nMAssay Description:Competitive inhibition of C-terminal His6-tagged recombinant SARS coronavirus 3C-like protease trans-cleavage activity expressed in Escherichia coli ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataIC50:  4.21E+4nMAssay Description:Inhibition of C-terminal His6-tagged recombinant SARS coronavirus 3C-like protease trans-cleavage activity expressed in Escherichia coli BL21 (DE3) u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataIC50:  8.59E+3nMAssay Description:Inhibition of human recombinant BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataIC50:  1.12E+5nMAssay Description:Inhibition of SARS coronavirus 3C-like protease cis-cleavage activity transfected in african green monkey Vero cells using SAVLQSGFRK as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed