BDBM50206434 1,2-Anthraquinonediol::1,2-dihydroxy-9,10-anthraquinone::1,2-dihydroxyanthra-9,10-quinone::1,2-dihydroxyanthracene-9,10-dione::Alizarin B::Alizarin Red::CHEMBL55814::Turkey Red::US20230364057, Compound 256::alizarin

SMILES Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O

InChI Key InChIKey=RGCKGOZRHPZPFP-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50206434   

TargetCytochrome P450 1B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataKi:  500nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in Escherichia coli coexpressing human NADPH-cytochrome P450 reductase using 7-ethoxyresorufin as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity to Bcl-2 after 30 mins by florescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataKi:  1.62E+3nMAssay Description:Binding affinity to Mcl-1 after 30 mins by florescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
The Florida International University Board Of Trustees

US Patent
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50:  3.75E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Instituto De Qu£Mica M£Dica (Iqm, Csic)

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase RNase HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Instituto De Qu£Mica M£Dica (Iqm, Csic)

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRmtA(Emericella nidulans)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50:  1.22E+6nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50:  1.16E+6nMAssay Description:Inhibition of human recombinant GST-PRMT1 expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University

Curated by ChEMBL
LigandPNGBDBM50206434(1,2-Anthraquinonediol | 1,2-dihydroxy-9,10-anthraq...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed