BDBM50145767 AVPIAQKSEK-FAM::CHEMBL404788

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCNC(=O)c1c(cccc1-c1c2ccc(O)cc2oc2cc(=O)ccc12)C(=O)ON1C(=O)CCC1=O)C(O)=O

InChI Key InChIKey=UIHIJARXXMWKOD-UVBGQCGDSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145767   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145767(AVPIAQKSEK-FAM | CHEMBL404788)
Affinity DataKd:  240nMAssay Description:Dissociation constant towards X-linked inhibitor of apoptosis (XIAP) BIR3 protein was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145767(AVPIAQKSEK-FAM | CHEMBL404788)
Affinity DataIC50:  2.80E+3nMAssay Description:Compound was tested for inhibiotry activity towards XIAP BIR3 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50145767(AVPIAQKSEK-FAM | CHEMBL404788)
Affinity DataIC50:  2.83E+3nMAssay Description:Compound was tested for inhibiotry activity towards XIAP BIR3 proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed