BDBM50009248 (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide::(2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide::3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide::3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide(Cerulenin)::CERULENIN::CHEMBL45627
SMILES C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O
InChI Key InChIKey=GVEZIHKRYBHEFX-NQQPLRFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50009248
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of F13-A in human plasma assessed as inhibition of fibrin clot formation by biotin incorporation assay in presence of 1 mM reduced GSHMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of FAS in human ZR-75-1 cells by spectrophotometryMore data for this Ligand-Target Pair
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.50E+6nMAssay Description:The compound was tested for its affinity against HIV-2 protease (in vitro)More data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested for its affinity against HIV-1 protease in vitroMore data for this Ligand-Target Pair