BDBM50250467 CHEMBL517637::Cirsimarin

SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=RETJLKUBHXTIGH-FZFRBNDOSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250467   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50250467(CHEMBL517637 | Cirsimarin)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Inifta (Unlp, Cct La Plata-Conicet)

Curated by ChEMBL
LigandPNGBDBM50250467(CHEMBL517637 | Cirsimarin)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of rat lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50250467(CHEMBL517637 | Cirsimarin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed