BDBM86207 CAS_50-36-2::COCAINE::NSC_446220

SMILES C[N@]1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)c3ccccc3)C(=O)OC

InChI Key InChIKey=ZPUCINDJVBIVPJ-UHFFFAOYSA-N

Data  7 KI

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 86207   

TargetNorepinephrine transporter(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  119nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Duquesne University

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  128nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  177nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  219nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Duquesne University

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  275nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  469nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Duquesne University

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  555nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
University of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM86207(NSC_446220 | CAS_50-36-2 | COCAINE)
Affinity DataKi:  2.42E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed