BDBM50308520 CHEMBL603622::cyclophostin

SMILES CO[P@]1(=O)OC[C@H]2COC(=O)C2=C(C)O1

InChI Key InChIKey=OMPQJMDGDAAXPE-NPMWZIQKSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308520   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataKi:  140nMAssay Description:Irreversible inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of AChE by modified Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50:  45nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50:  40nMAssay Description:Inhibition of human AChE at pH 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Musca domestica)
University Of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of housefly CSMA AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50308520(CHEMBL603622 | cyclophostin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat hormone sensitive lipase assessed as oleic acid release from [3H]triolein by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed