BDBM22883 CHEMBL12344::Dimaprit::[3-(carbamimidoylsulfanyl)propyl]dimethylamine
SMILES CN(C)CCCSC(N)=N
InChI Key InChIKey=OLHQOJYVQUNWPL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 22883
Affinity DataKi: 90nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in SK-NM-C cellsMore data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 316nM ΔG°: -9.22kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Affinity DataKi: 2.51E+4nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.59E+3nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Affinity DataKd: 2.63E+4nMAssay Description:Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligandMore data for this Ligand-Target Pair