BDBM36351 CID148124::Docetaxel
SMILES [H][C@]12[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C(C)=C([C@@H](O)C(=O)[C@]1(C)[C@@H](O)C[C@H]1OC[C@@]21OC(C)=O)C3(C)C
InChI Key InChIKey=ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 36351
Affinity DataKi: 2.91E+5nM IC50: 6.65E+5nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMpH: 6.8Assay Description:Cell proliferation assay for ispinesib-resistant DCT116-D130V cellMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataKd: 0.820nMAssay Description:Displacement of radiolabeled EGF from EGF receptor expressed in human MX1 cellsMore data for this Ligand-Target Pair
TargetGrowth hormone-releasing hormone receptor(Homo sapiens (Human))
Veterans Affairs Medical Center
Curated by ChEMBL
Veterans Affairs Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Displacement of [125I]JV1-42 from GHRH receptor expressed in human MX1 cellsMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of MDP-induced human NOD2 signaling expressed in HEK-Blue cells preincubated for 3 hrs followed by MDP-stimulation for 20 hrs by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMpH: 6.8Assay Description:Cell proliferation assay for wild-type cellsMore data for this Ligand-Target Pair