BDBM50070942 (-)-Epigallocatechin gallate::(-)-Epigallocatechin-3-o-gallate::(-)-epigallocatechin 3-gallate::(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate::CHEMBL297453::EGCG::Epigallocatechin 3-gallate::Epigallocatechin monogallate, B::cid_65064
SMILES Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1
InChI Key InChIKey=WMBWREPUVVBILR-WIYYLYMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 98 hits for monomerid = 50070942
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of Plasmodium falciparum ENR in presence of triclosanMore data for this Ligand-Target Pair
TargetOrphan methyltransferase M.SssI(Spiroplasma monobiae strain MQ-1)
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Inhibition of Plasmodium falciparum ENR using crotonyl-CoA substrateMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Affinity DataKi: 186nMAssay Description:Inhibition of Plasmodium falciparum ENR using NADH substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Dundee
Curated by PDSP Ki Database
University Of Dundee
Curated by PDSP Ki Database
Affinity DataKi: 335nMAssay Description:Displacement of NLWAAQRYGRELRRMSD-K(FITC)-FVD from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.28E+3nMAssay Description:Non-competitive inhibition of N-terminal full length NADK (unknown origin) expressed in Escherichia coli BL21(DE3) cells by HDX-MS analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Oregon State University
Curated by ChEMBL
Oregon State University
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of MET kinase by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.36E+4nMAssay Description:Displacement of [3H]-CP5594 from human recombinant CB1 receptor expressed in Chem1 cells after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.36E+4nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.28E+4nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Horizon Discovery
Curated by ChEMBL
Horizon Discovery
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length Pin1 (unknown origin) using WFY(pS)PR-pNA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 5.89E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataEC50: 727nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.80E+3nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
TargetCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 2.70E+4nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 2.10E+4nMpH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Montclair State University
Curated by ChEMBL
Montclair State University
Curated by ChEMBL
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of HSP90 (unknown origin) by luciferase refolding assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of amyloid beta1-42 (unknown origin) aggregation assessed as amyloid fibril formation tested after 17 hrs by thioflavin T fluorescence met...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Shizuoka And Global Coe Program
Curated by ChEMBL
University Of Shizuoka And Global Coe Program
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 757nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BACE1 using Rh-EVNLDAEFK-Quencher as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged human recombinant DNMT1 expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biot...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Csiro Manufacturing Flagship (Biomedical)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by ChEMBL
The Hong Kong Polytechnic University
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
University Of Dundee
Curated by PDSP Ki Database
University Of Dundee
Curated by PDSP Ki Database
Affinity DataIC50: 330nMAssay Description:Inhibition of rat Dyrk1A using Woodtide as substrate after 40 mins by P81 membrane assay in presence of [33P]-g-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+6nMAssay Description:Inhibition of human salivary alpha-amylase using rice starch as substrate after 12 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant GST-tagged p300 (unknown origin) using histone H4 peptide substrate assessed as reduction in NADH formation by spectrophoto...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant GST-tagged CBP (unknown origin) using histone H4 peptide substrate assessed as reduction in NADH formation by spectrophotom...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of recombinant PCAF (unknown origin) using histone H4 peptide substrate assessed as reduction in NADH formation by spectrophotometric anal...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of recombinant TIP60 (unknown origin) using histone H4 peptide substrate assessed as reduction in NADH formation by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Oregon State University
Curated by ChEMBL
Oregon State University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MET kinaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of p38alpha after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
The Second Military Medical University
Curated by ChEMBL
The Second Military Medical University
Curated by ChEMBL
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of GST-tagged human DYRK1A using dephosphorylated MBP as substrate after 10 mins by Kinase-Glo plus luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant rat SE(squalene epoxidase)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Toledo
Curated by ChEMBL
University Of Toledo
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology
Curated by ChEMBL
National Institute Of Immunology
Curated by ChEMBL
Target3-oxoacyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair