BDBM50104600 (S)-3-{[(R)-1-(3-Piperidin-4-yl-propionyl)-piperidine-3-carbonyl]-amino}-3-pyridin-3-yl-propionic acid::3-{[1-(3-Piperidin-4-yl-propionyl)-piperidine-3-carbonyl]-amino}-3-pyridin-3-yl-propionic acid (RWJ 53308 (Elarofiban))::CHEMBL87728::Elarofiban::RWJ-53308
SMILES OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C1)C(=O)CCC1CCNCC1)c1cccnc1
InChI Key InChIKey=ABNXKGFLZFSILK-MOPGFXCFSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50104600
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human vitronectin binding to immobilized Alpha v beta-3More data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3More data for this Ligand-Target Pair