BDBM7972 CHEMBL816::ethane-1,2-diamine::ethylenediamine

SMILES NCCN

InChI Key InChIKey=PIICEJLVQHRZGT-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 8 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7972   

TargetGlutaminyl-peptide cyclotransferase(Mus musculus (mouse))
Probiodrug

LigandPNGBDBM7972(CHEMBL816 | ethane-1,2-diamine | ethylenediamine)
Affinity DataKi:  2.20E+7nM ΔG°:  -2.30kcal/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM7972(CHEMBL816 | ethane-1,2-diamine | ethylenediamine)
Affinity DataIC50:  1.55E+7nMAssay Description:Inhibition of [3H]-farnesyl pyrophosphate binding to human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed