BDBM50439621 GANETESPIB::STA-9090
SMILES CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3n(C)ccc3c2)c(O)cc1O
InChI Key InChIKey=RVAQIUULWULRNW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50439621
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of human HSP90More data for this Ligand-Target Pair
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of TRAP1 (unknown origin)More data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of GRP94 (unknown origin)More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 24nMAssay Description:Binding affinity to HSP90 (unknown origin) by fluorescence quenching methodMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation (Dgmif)
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HSP90alpha (unknown origin) incubated for 24 hrs in presence of 1-FITC3 probe by fluorescence polarization assayMore data for this Ligand-Target Pair