BDBM50102454 Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu-Har(Et2)-Pro-DAla-NH2::CHEMBL1251::GANIRELIX ACETATE::Ganirelix::Ganirelix acetate injection::RS-26306

SMILES CCNC(NCCCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(NCC)=NCC)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O)=NCC

InChI Key InChIKey=GJNXBNATEDXMAK-PFLSVRRQSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102454   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102454(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu...)
Affinity DataKd:  0.501nMAssay Description:Competitive antagonism of GnRH-induced response in the reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50102454(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu...)
Affinity DataIC50:  3.60nMAssay Description:Antagonism of human GnHR receptor, determined in a reporter gene assay in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed