BDBM50311743 CHEMBL487992::GARTANIN

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc3c(-[#8])ccc(-[#8])c3c(=O)c2c1-[#8]

InChI Key InChIKey=OJXQLGQIDIPMTE-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311743   

TargetSialidase(Clostridium perfringens)
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataKi:  3.60E+3nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNEDD8-conjugating enzyme Ubc12(Homo sapiens)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of Ubc12 (unknown origin)-neddylation incubated for 30 mins in presence of ATP by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase(Clostridium perfringens)
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311743(CHEMBL487992 | GARTANIN)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed