BDBM50242278 CHEMBL506069::Geraniin::geraniiin

SMILES Oc1cc(cc(O)c1O)C(=O)O[C@@H]1O[C@@H]2COC(=O)c3cc(O)c(O)c(O)c3-c3c(O)c(O)c(O)cc3C(=O)O[C@H]3[C@@H]2OC(=O)C2=CC(=O)[C@]4(O)Oc5c(O)c(O)cc(c5[C@H]2C4(O)O)C(=O)O[C@@H]13

InChI Key InChIKey=JQQBXPCJFAKSPG-SVYIMCMUSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50242278   

TargetSqualene monooxygenase(Rattus norvegicus)
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataEC50:  10nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataEC50:  6.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of ACE by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed