BDBM50403688 HAPALOSIN
SMILES CCCCCCC[C@H]1OC(=O)C[C@@H](O)[C@H](Cc2ccccc2)N(C)C(=O)[C@@H](OC(=O)[C@H]1C)C(C)C
InChI Key InChIKey=NJNAHFYVTBZQHU-LFFUDGMSSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50403688
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Multidrug-resistant reversal activity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycopr...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.13E+4nMAssay Description:Evaluated for cytotoxicity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycoprotein) in t...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Multidrug-resistant reversal activity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycopr...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Evaluated for cytotoxicity using P388/VMDRC.04 cells (a subline of P388 murine leukemia cells expressing human recombinant human P-glycoprotein) in t...More data for this Ligand-Target Pair