BDBM21686 3-(4-hydroxybutyl)-6-(3-ethyl-4-methylanilino)uracil::6-[(3-ethyl-4-methylphenyl)amino]-3-(4-hydroxybutyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione::CHEMBL327687::HB-EMAU::HBEMAU
SMILES CCc1cc(Nc2cc(=O)n(CCCCO)c(=O)[nH]2)ccc1C
InChI Key InChIKey=DKZBKKHAGYCGJG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 21686
Affinity DataKi: 55nMAssay Description:Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Inhibitory activity against DNA polymerase IIIC from Bacillus subtilis was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 63nM ΔG°: -9.98kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+5nM ΔG°: -5.45kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
Affinity DataKi: >1.01E+6nM ΔG°: >-4.25kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
Affinity DataKi: >1.01E+6nM ΔG°: >-4.15kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
Affinity DataKi: >1.01E+6nM ΔG°: >-4.25kcal/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair