BDBM50073316 CHEMBL114715::INOGATRAN::{(R)-1-Cyclohexylmethyl-2-[(S)-2-(3-guanidino-propylcarbamoyl)-piperidin-1-yl]-2-oxo-ethylamino}-acetic acid::{1-Cyclohexylmethyl-2-[2-(3-guanidino-propylcarbamoyl)-piperidin-1-yl]-2-oxo-ethylamino}-acetic acid(inogatran)::{[(1R)-2-((2S)-2-{[(3-{[AMINO(IMINO)METHYL]AMINO}PROPYL)AMINO]CARBONYL}PIPERIDINYL)-1-(CYCLOHEXYLMETHYL)-2-OXOETHYL]AMINO}ACETIC ACID
SMILES NC(=N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(O)=O
InChI Key InChIKey=CDPROXZBMHOBTQ-SJORKVTESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50073316
Affinity DataKi: 4.20nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against Thrombin.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:The inhibitory activity of the compound was tested against thrombin (IIa)More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Nv Organon Scientific Development Group
Curated by ChEMBL
Nv Organon Scientific Development Group
Curated by ChEMBL
Affinity DataKi: 675nMAssay Description:The inhibitory activity of the compound was tested against trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+4nMAssay Description:In vitro for the inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition against platelet aggregation without interacting directly with the nucleophilic serine of thrombin.Checked by AuthorMore data for this Ligand-Target Pair