BDBM50293169 CHEMBL523927::kendomycin

SMILES C[C@H]1[C@H]2CC[C@H](C)\C=C(C)\C[C@@H](C)C[C@H](C)[C@]3(O)OC4=C(C)C(=O)C(=O)C([C@H](O2)[C@H](C)[C@H]1O)C4=C3

InChI Key InChIKey=OPRMEAXDCSIVJB-NIXBLEKVSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293169   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  5.28E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  1.83E+6nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed