BDBM50053615 3-Chloro-Phenyl biguanide::CHEMBL13790::N-(3-chlorophenyl)imidodicarbonimidic diamide::m-chlorophenylbiguanidine

SMILES NC(=N)N=C(N)Nc1cccc(Cl)c1

InChI Key InChIKey=DIHXJZHAIHGSAW-UHFFFAOYSA-N

Data  1 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50053615   

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataKi:  17nMAssay Description:Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human 5-HT43A receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 5(Mus musculus)
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at human 5-HT43AB receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Virtua Drug

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at wild type mouse 5HT3A receptor expressed in Xenopus oocyte by two-electrode voltage patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataIC50:  1.91E+5nMAssay Description:Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectiinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed