BDBM50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23

SMILES CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O

InChI Key InChIKey=SLVMESMUVMCQIY-UHFFFAOYSA-N

Data  32 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 50131440   

TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  1.81nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  4.76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  7.94nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  9.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  13.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  18.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  69nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  71.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  79nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  79.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  90nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  157nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  159nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
University Of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataKi:  1.61E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataIC50:  550nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataIC50:  324nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataIC50:  316nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM50131440(10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulf...)
Affinity DataIC50:  324nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed