BDBM50428389 CHEMBL146816::Methyl 3-(4-Hydroxyphenyl)Acrylate::Methyl P-Hydroxycinnamate::Methyl Trans-P-Coumaric Acid::Methyl-P-Coumarate::P-Hydroxy Cinnamic Acid Methyl Ester

SMILES COC(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=NITWSHWHQAQBAW-QPJJXVBHSA-N

Data  6 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50428389   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  780nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  800nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  810nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  820nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  830nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataKi:  850nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of tyrosinase in neonatal human epidermal melanocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human tyrosinase after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428389(CHEMBL146816 | Methyl 3-(4-Hydroxyphenyl)Acrylate ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human tyrosinase after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed