BDBM50135288 (1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-1,2,3-triol::(1S,2R,3S,4R)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2,3-triol::CHEMBL129014::NORARISTEROMYCIN

SMILES Nc1ncnc2n(cnc12)[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O

InChI Key InChIKey=VFKHECGAEJNAMV-HETMPLHPSA-N

Data  4 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50135288   

TargetAdenosylhomocysteinase(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataKi:  160nMAssay Description:Inhibitory activity of the compound against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Plasmodium falciparum 3D7)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataKi:  180nMAssay Description:Inhibitory activity of the compound against P. falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataKi:  692nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity of the compound against human S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Plasmodium falciparum 3D7)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity of the compound against P. falciparum S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Plasmodium falciparum 3D7)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Plasmodium falciparum SAHHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant SAHHMore data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50135288((1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human SAHHMore data for this Ligand-Target Pair